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Influence of laterality in somatognostic functions of floorball players
Žarković, Dragana ; Nováková, Tereza (advisor) ; Vláčilová, Ivana (referee)
! Title of thesis : Influence of laterality in somatognostic functions of floorball players Demarcation of the issue : This thesis is dedicated to the influence of laterality in somatognostic functions of floorball players and it rates relation between these two phenomenons. It is a first research in this branch and sport, also, it informs about the coherence of these two phenomenons, from the point of view as a cause of sports injuries and also as a prevention of sports injuries. Justification : Athletes get injured frequently in many different situations. Often, we are dealing with an injury as a consequence, but not the real cause. Physical therapist should get oriented in this problematics to be more effective in the healing process of the athlete. To avoid such problems in adulthood, we should be more focused on the prevention just at the beginning of a sports career of a small athlete. No matter what sports level the athlete had achieved, we are focusing especially in one-sided sport activities. Aim of the thesis : The aim of thesis is to find out any coherence of the effect of one-sided sports, as floorball, to somatognostic functions of players at the age between 6 - 14 years old. Methodology of the thesis : Research is created in a form of descriptive - associative academic method. It is...
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Casuistics of physiotherapy care for patient diagnosed with cerebellar lesion after a brain hypoxia
Vyhnánek, Štěpán ; Reckziegelová, Petra (advisor) ; Křížková, Štěpánka (referee)
Title: Casuistics of physiotherapy care for patient diagnosed with cerebellar lesion after a brain hypoxia Goal: The goal of this work is data collection and processing of theoretical information on cerebellar ischemia and a preparation of casuistics of a patient with cerebellar hypoxia after heart attack. Summary: My thesis deals with cerebellar hypoxia after leaving sufferd from loss of heart as a result of heart attack. Thesis is divided in to parts. The first part, a theoretical one, describes anatomical and functional structure of the cerebellum, a brief description of ISCH and treatment options. This part also contains a description of rehabilitation methods used in patients with cerebellar syndrome. The second part of my thesis, a practical one, is focused on a precise description of the work with the patient after having suffered from loss of cerebellar hypoxia, I have collaborated with on inpatient department of regional hospital in Kladno from January 5th to January 22nd, 2016. The practical part contains results of patient's examination in time of admision to hospital and in time of release from hospital and a description of individual therapautical units (used methods, the progress of the therapy and the success of treatment). Keywords: heart attack, cerebellum, rehabilitation
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Manifestation of cerebellar dominance in the form of extinction physiological syndrome on upper and lower limbs and its relationship to human laterality
Rybář, Adam ; Musálek, Martin (advisor) ; Tlapáková, Eva (referee)
1 Title: Manifestation of cerebellar dominance in the form of extinction physiological syndrome on upper and lower limbs and its relationship to human laterality. Objectives: The aim of this diploma thesis is to determinate size of relationship between manifestation of cerebellar dominance in the form of extinction physiological syndrome and preference of limbs. Methods: A total of 27 individuals (male and female students of UK FTVS) were involved in the current quantitative research. We used indicators which were selected from Musalek's test battery (2013) to assess limb preferences. The evaluation of joint passivity asymmetry was based on angle and time parameters during walk and during controlled falls of forearm and shank on a constructed fall-machine. The movement was registered in real time by Qualisys Motion Capture System. For data analysis, descriptive statistics methods, paired t-test, level of statistical and substantive significance (Cohen's d) and tetrachoric coefficient of correlation were used. Results: Our research suggests that there is no significant difference in joint passivity when comparing preferred and non preferred limbs. Though it is necessary to take into consideration specifics and the size of research sample in which everybody was an active athlete. The result of tetrachoric...
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Circadian system and it's changes in Lurcher mutant mice
Boubín, Josef ; Bendová, Zdeňka (advisor) ; Jelínková, Dana (referee)
The main topic of this thesis are changes in Circadian rhythms caused by cerebellar disorders. Mice with Lurcher mutation, which have specifically degenerated Purkinje cells layer, were choosen as animal model. Our results show that mutation of the glutamate receptor GluRδ2, which causes gradual degeneration of Purkinje cells, leads to damage of Circadian system. Mice with this mutation have reduced capability to adapt to external conditions in different light modes. They are also showing increased variability in endogenous cycle. The mice are also unable to show anticipatory behavior in time-restricted feeding. Compared to control group, affected mice do not show significant rhythm in levels of protein of Bmal1 gene in suprachiasmatic nuclei, paraventricular nuclei nor in habenula. Phosphorylated kinases ERK1/2 and GSK3ß also had distorted rhythms in suprachiasmatic nuclei. Because Circadian oscillations in locomotor activity are partly preserved, Circadian system is likely not damaged on molecular level. Cerebellar mutation hampers synchronization between suprachiasmatic nuclei of neurons and can also affect processes in the ventromedial hypothalamus regulating food intake. Our findings are the first to suggest functional interactions between cerebellum and Circadian pacemaker in suprachiasmatic...
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Stimulation of the Child with dandy-walker syndrome: Therasuit Method
Střelcová, Martina ; Hájková, Vanda (advisor) ; Šumníková, Pavlína (referee)
1 ABSTRACT This diploma issue brings the new knowledge from the physiotherapeutical and special educational intervention like diagnostics and therapy by multiple disabeled child with Dandy-Walker syndrom. Therapeutical method which we deals with is called TheraSuit. One of the aims of this work is to find out which areas of the psychomotor development is primary focused on TheraSuit. We would like to know what is its advantage over the use of standard rehabilitation techniques in outpatient care. Research methods are semistructured interview with the mother of the respondent, observation, special educational and physiotherapeutic diagnostics and aplication of their techniques. Effectiveness of these remedial procedures we are verifying by standardized tests, kineziological analyzes, assesements of self-sufficiency and gross motors skills at the end of every rehabilitation. This research confirms efficiency of exercises with TheraSuit Method particurally in speed of locomotion development by our respondent. However it is not possible to neglect of outpatient treatment with the use of usual therapeutic process especially because of their easy application at home. Regural health physiotherapeutic and special educational activity is the foundation of succsess of every rehabilitaion. KEY WORDS Stimulation,...
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Changes motor functions in mouse model of cerebellar degeneration in the course of the ontogenesis
Šalomová, Martina ; Jelínková, Dana (advisor) ; Kubik-Zahorodna, Agnieszka (referee)
The cerebellum affects a number of important and complex processes in the organism. It ensures coordination, motor learning and plays an important role in cognitive and affective functions. In the case of cerebellar degeneration, we find not only the movement disorders but also behavioral abnormalities, collectively referred to as cognitive-affective syndrome. The aim of this work was to investigate motor functions during ontogenesis in animal models of hereditary cerebellar degeneration - mutant mice Lurcher and Purkinje cell degeneration using the device for quantitative gait analysis and rotarod. In addition, the effect of physical activity on the extent of ataxia and manifestations in classical behavioral tests was monitored. The results confirmed significant differences in motor skills between mutant and healthy mice; differences were also observed in some gait parameters, especially in walking speed and parameters that correlate with it. The motor functions of most groups of mice did not change during ontogenesis, pcd mice deteriorated their performance on the rotarod. The effect of physical activity was not found, with the exception of Forced swimming test. Physical activity of set intensity did not have any beneficial effect on the motoric manifestations of the mice.
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Molecular subgroups of medulloblastoma: the current consensus
Jarošová, Šárka ; Zíková, Martina (advisor) ; Nedvědová, Tereza (referee)
Medulloblastoma is the most common malignant brain tumor in children. In recent years, there has been a steady improvement in understanding of genetic and molecular heterogeneity of this tumor, that has led to better prognosis and improved targeted therapies. This thesis summarizes recent advances in molecular sub-grouping, and the associated gene mutation and copy number variations in medulloblastoma.
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Physiotherapeutic approaches in cerebelar syndrome
Chytrová, Kateřina ; Zumrová, Alena (advisor) ; Zounková, Irena (referee)
Cerebellar ataxia syndrome is treated in different ways depending on source of its origin. In the case of an acquired disease the primary treatment is focused on eliminating the basic disease and physiotherapy influences its aftermaths. In the case of genetically determined disease physiotherapy is an essential treatment, although it only treats symptoms, and it can distinctly affect the patient's life quality. The work is designed as a basis for a planned guideline for the rehabilitation of cerebellar disorders in the Hereditary Ataxia Center FHN Motol. It summarizes more than eighty, mostly foreign, studies that deal with the possibility to influence cerebellar symptoms with physiotherapeutic procedures and discusses the approach of 5 specialized worlds' centers for cerebellar diseases. In conclusion there are case reports of six patients with cerebellar symptoms and an analysis of their existing physiotherapy. Powered by TCPDF (www.tcpdf.org)
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Characteristics of the nervous system of mice with a Lurcher mutation
Boubín, Josef ; Bendová, Zdeňka (advisor) ; Tůma, Jan (referee)
The glutamate receptor δ 2 (GluRδ2) is expressed in dendrites of Purkinje cells localized in the cerebellar cortex. Correct function of GluRδ2 is necessary for cerebellar development, synapse formation between parallel fibers of the granular and Purkinje cells and for inducing long term depression important in memory formation. Lurcher mutation, localized to 6th autosomal chromosome, transforms GluRδ2 into constitutively open ion channel by amino acid substitution in third transmembrane domain. As a result, almost complete disappearance of Purkinje cells population and a large degeneration of granular cells and olivary neurons occurs. Mice impaired by Lurcher mutation have lower body weight and reduced litter size. Fertility of males is not affected. Lurcher mutants display extensive behavioral deficits. Mice suffer from ataxia typical for cerebellar neurodegenerations. They have reduced physical performance, impaired spatial orientation and learning capabilities. The aim of this work is to summarize recent knowledge about Lurcher mutation from molecular basis to behavioral manifestation. Specific characteristics of this degeneration allow us to investigate influences of neurodegenerative cerebellar disorders on cognitive functions of the brain as a whole, study causing factors and treatment...
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